While the cabin is similar to the standard SL, AMG versions have bespoke instruments and many of the materials are different, giving the car a more sporty feel. New features from 2008 are a reader for music files on SD card, the availability of digital radio as an option and a switch to a different premium audio system provider.

Being a two seater allows pretty generous room in the cabin, although you have to be agile to get in and out of the low body with the roof up. The seats are firm, but comfortable and are electrically adjustable while the metal roof is fully electric and can be chosen with a glass panel overhead rather than steel, allowing the cabin to be bathed in sunlight even on the coldest days.

However, since April 2008 the SL has been available with the Airscarf feature also found on the SLK which warms the neck area with fans and a heating element in the head restraints. The SL AMG is hardly affected by wind noise with the roof up, and buffeting is minimised with the roof down thanks to a pop-up deflector. Tyre noise is more noticeable, however.